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cell modeling in COMSOL

Posted 3 dic 2015, 18:01 GMT-5 Fluid & Heat, Microfluidics Version 5.1 0 Replies

Nikki Davidoff
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I am trying to model cells flowing through a 3D microfluidic channel in comsol. I have been having issues getting the results to match what I see experimentally, but I am not sure what factors I am missing.

The velocity profile from creeping flow looks appropriate, but the particle tracing is not even close to what I've obtained experimentally. I assume that if the particles (cells) touch the bottom surface of the microfluidic channel that they stick; however none of the particles reach the bottom of the channel by the end of my simulation. Experimentally I see between 100 and 2000 cells attaching to that surface, depending on the conditions.

Any help would be greatly appreciated.

The file size is too large to upload, but I can share it via email if anyone thinks they can help.
0 Replies Last Post 3 dic 2015, 18:01 GMT-5
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Hello Nikki Davidoff

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